Different Patterns of Kidney Toxicity after Subacute Administration of Na-Nitrilotriacetic Acid and Fe-Nitrilotriacetic Acid to Wistar Rats
نویسندگان
چکیده
منابع مشابه
Bioassays of nitrilotriacetic acid (NTA) and nitrilotriacetic acid, trisodium salt, monohydrate (Na3-NTA-H2O) for possible carcinogenicity.
Bioassays for the carcinogenicity of nitrilotriacetic acid, trisodium salt, monohydrate (Na3-NTA-H2O) were conducted at Stanford Research Institute (SRI), using Fischer 344 rats and at Litton Bionetics, Inc. (LBI), using both Fischer 344 rats, and B6C3F1 mice. Similar bioassays using rats and mice, were conducted at LBI on the free acid, nitrilotriacetic acid (NTA). Each chemical was mixed in r...
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Aminopolycarboxylic acids are ubiquitous in natural waters and wastewaters. They have the ability to form very stable water-soluble complexes with many metallic di- or trivalent ions. The iron complex nitrilotriacetic acid-Fe(III) (FeNTA) has been previously shown to increase drastically the rate of photo- and biodegradation of 2-aminobenzothiazole, an organic pollutant, by Rhodococcus rhodochr...
متن کاملLuteolin ameliorates ferric nitrilotriacetic acid induced renal toxicity and tumor promotional response in rat.
Ferric nitrilotriacetic acid (Fe-NTA) (9 mg Fe/kg body weight, i.p.) caused significant depletion in the detoxification and antioxidant enzyme armory with concomitant elevation in renal lipidperoxidation, serum toxicity markers viz. creatinine, blood urea nitrogen, hydrogen peroxide generation, ornithine decarboxylase activity and [3H] thymidine incorporation into renal DNA in wistar rats. Howe...
متن کاملNitrilotriacetic acid: a novel reducing agent for synthesizing colloidal gold.
We report for the first time that nitrilotriacetic acid (NTA) is an effective reductant for the preparation of stable dispersions of uniform gold nanoparticles. The method described is capable of generating stable sols with a metal concentration as high as 1.5×10(-3)moldm(-3). The size of gold nanoparticles can be tuned from 10 to 160 nm by adjusting the stoichiometric excess of NTA. For a cons...
متن کاملStudy on the Interaction of Dioxovanadium(V) with Nitrilotriacetic Acid at Different Ionic Strengths by Using Extended Debye-Hiickel Equation
In this research complexation of dioxovanadium(V) with nitrilotriacetic acid (NTA) at differentionic strengths (0.1 to 1.0 mol dm-3) of sodium perchlorate as supporting electrolyte and pH rangeof 1.00-2.50 at 25 °C has been investigated by a combination of potentiometric and UVspectrophotometric measurements. Stability constants of two species, V0211L- and VO2H2L havebeen calculated. Ionic stre...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 1998
ISSN: 1096-6080
DOI: 10.1006/toxs.1998.2507